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Emphysema is a chronic lung disease that damages the air sacs (alveoli) in the lungs, making it difficult to breathe out properly. The damage reduces the lungs' ability to transfer oxygen into the bloodstream and often causes air to become trapped inside the lungs. Emphysema is one of the main conditions included in chronic obstructive pulmonary disease (COPD).
The most common cause of emphysema is cigarette smoking, although long-term exposure to air pollution, harmful workplace substances, and certain genetic conditions can also contribute to its development.
Emphysema treatment focuses on relieving breathlessness, improving lung function as much as possible, preventing flare-ups, and maintaining a better quality of life. Although existing lung damage is generally permanent, appropriate treatment can help manage symptoms and slow disease progression.
Shortness of breath, especially during physical activity
Persistent cough
Wheezing
Chest tightness
Difficulty breathing out completely
Fatigue and weakness
Reduced ability to exercise
Frequent respiratory infections in some patients
Symptoms usually develop gradually and may become more severe as the disease progresses.
Bronchodilator medications: Inhaled medicines help relax the muscles around the airways, making breathing easier. Depending on the severity of symptoms, doctors may prescribe short-acting or long-acting bronchodilators.
Inhaled corticosteroids: These medicines may be recommended for selected patients with COPD who have frequent exacerbations or certain other clinical features. They are not routinely required for every patient with emphysema.
Smoking cessation: Stopping smoking is one of the most important steps in slowing further lung damage. Medical support, counselling, and approved smoking-cessation treatments may help.
Oxygen therapy: Supplemental oxygen may be prescribed for patients with persistently low blood oxygen levels. It should be used according to medical assessment and prescription.
Pulmonary rehabilitation: Supervised exercise, breathing techniques, education, and energy-management strategies can help reduce breathlessness and improve exercise capacity.
Lung volume reduction procedures: Selected patients with severe emphysema may benefit from procedures that remove or reduce the function of severely damaged lung areas, including certain bronchoscopic procedures.
Lung transplantation: In carefully selected patients with advanced emphysema, lung transplantation may be considered after specialist evaluation.
Doctors may recommend several investigations to confirm the diagnosis and assess disease severity, including:
Medical history and physical examination
Spirometry and other pulmonary function tests
Chest X-ray
CT scan of the chest
Oxygen-level measurement
Blood tests when clinically indicated
Testing for alpha-1 antitrypsin deficiency in appropriate patients
These tests help doctors understand the extent of lung damage and select the most suitable treatment plan.
Stop smoking and avoid secondhand smoke.
Reduce exposure to dust, fumes, and air pollution.
Use prescribed inhalers correctly.
Stay physically active within your healthcare professional's recommendations.
Maintain a balanced diet and a healthy weight.
Discuss recommended influenza, COVID-19, and pneumococcal vaccinations with your doctor.
Seek medical advice if cough, mucus production, or breathlessness suddenly worsens.
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